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Complex Ophthalmic Dosage Forms: Advances in Biomedical Applications and Future Perspectives
This book, Complex Ophthalmic Dosage Forms: Advances in Biomedical Applications and Future Perspectives, offers a detailed overview of the latest innovations in ophthalmic drug delivery. Beginning with the fundamentals of ocular drug delivery systems and the anatomy of the eye, this book provides an exploration of drug delivery to both the anterior and posterior segments. A dedicated chapter on the fixed-dose combination approach examines its application in ocular diseases, highlighting both its therapeutic potential and associated challenges. Furthermore, the book delves into key aspects of ophthalmic product development, including reverse engineering, the role of preservatives, and the application of Quality by Design (QbD) principles. It includes discussions on the safety of nanoformulations, as well as an in-depth analysis of emerging nano-assisted platforms in ocular drug delivery, highlighting both opportunities and safety concerns. Recognizing the importance of packaging a dedicated chapter explores the critical role of sterility in ocular products, detailing sterility validation processes to ensure product safety and efficacy. This is followed by a thorough discussion on packaging, including the selection of appropriate containers and closure systems. Given that an optimized packaging system is essential for maintaining the stability, sterility, and overall quality of ophthalmic products, this section highlights key considerations in designing effective packaging solutions. Additionally, the book delves into regulatory considerations, challenges in clinical translation, and potential future developments that may redefine ophthalmic therapeutics.></p>
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