El código de la vida

El código de la vida

Walter Isaacson vuelve a fascinarnos, esta vez con la historia de Jennifer Doudna, Premio Nobel de Química 2020, y el avance científico más importante del último siglo.Hay una revolución en marcha, una tecnología prodigiosa que nos va a permitir curar enfermedades, derrotar virus y tener hijos más sanos. A su cabeza está la reciente premio Nobel Jennifer Doudna y sus colegas, protagonistas del nuevo libro de Walter Isaacson. Aunque su profesor de instituto le advirtió que las niñas no podían ser científicas, su búsqueda apasionada de los mecanismos ocultos de la vida y su voluntad por convertir descubrimientos en inventos llevaron a Jennifer Doudna a participar en el avance más importante en el ámbito de la biología desde el descubrimiento de la doble hélice del ADN. Con su equipo, transformó una curiosidad de la naturaleza en una herramienta que cambiará el rumbo del ser humano. El CRISPR, una técnicafácil de usar que permite modificar el ADN, lo que abre un mundo nuevo de milagros médicos pero también de cuestiones morales.El desarrollo del CRISPR (y la carrera por encontrar la vacuna del coronavirus) acelerarán nuestra transición a la siguiente gran revolución. Los últimos cincuenta años han sido una era digital basada en el microchip, el ordenador e internet. Ahora comienza la revolución de las ciencias de la vida. A los estudiantes de código digital se les unirán los que estudian el código genético.¿Deberíamos usar nuestras nuevas capacidades para hacernos menos vulnerables a los virus? ¿Y para prevenir la depresión? ¿Deberíamos aceptar que las familias que se lo puedan permitir mejoren la constitución física o la inteligencia de sus hijos? Tras dirigir el equipo que descubrió la tecnología CRISPR, Doudna ha liderado los debates en torno a estas cuestiones morales.Obtuvo, junto con su colaboradora Emmanuelle Charpentier, el Premio Nobel de Química en 2020. Su historia es una apasionanteaventura que atraviesa las maravillas más profundas de la naturaleza, de los orígenes de la vida al futuro de nuestra especie.La crítica ha dicho...«El premio de este año tiene que ver con la idea de reescribir el código de la vida. Estas tijeras genéticas han llevado a la ciencia a una nueva era.»Anuncio del Premio Nobel de Química 2020«Un libro extraordinario que profundiza en una de las tecnologías biológicas más innovadoras de nuestro tiempo y las personas que la crearon. Brillante es una lectura absolutamente necesaria para nuestra era.»Siddhartha Mukherjee«Un libro vital sobre la última gran innovación científica, y otra biografía de primer nivel de Isaacson.»Kirkus Weekly

The Undoing Project: A Friendship That Changed Our Minds

The Undoing Project: A Friendship That Changed Our Minds

“Brilliant. . . . Lewis has given us a spectacular account of two great men who faced up to uncertainty and the limits of human reason.” —William Easterly, Wall Street Journal Forty years ago, Israeli psychologists Daniel Kahneman and Amos Tversky wrote a series of breathtakingly original papers that invented the field of behavioral economics. One of the greatest partnerships in the history of science, Kahneman and Tversky’s extraordinary friendship incited a revolution in Big Data studies, advanced evidence-based medicine, led to a new approach to government regulation, and made much of Michael Lewis’s own work possible. In The Undoing Project, Lewis shows how their Nobel Prize–winning theory of the mind altered our perception of reality.

Demystifying Big Data, Machine Learning, and Deep Learning for Healthcare Analytics (Enhanced Edition)

Demystifying Big Data, Machine Learning, and Deep Learning for Healthcare Analytics (Enhanced Edition)

Demystifying Big Data, Machine Learning, and Deep Learning for Healthcare Analytics presents the changing world of data utilization, especially in clinical healthcare. Various techniques, methodologies, and algorithms are presented in this book to organize data in a structured manner that will assist physicians in the care of patients and help biomedical engineers and computer scientists understand the impact of these techniques on healthcare analytics. The book is divided into two parts: Part 1 covers big data aspects such as healthcare decision support systems and analytics-related topics. Part 2 focuses on the current frameworks and applications of deep learning and machine learning, and provides an outlook on future directions of research and development. The entire book takes a case study approach, providing a wealth of real-world case studies in the application chapters to act as a foundational reference for biomedical engineers, computer scientists, healthcare researchers, and clinicians. Provides a comprehensive reference for biomedical engineers, computer scientists, advanced industry practitioners, researchers, and clinicians to understand and develop healthcare analytics using advanced tools and technologies Includes in-depth illustrations of advanced techniques via dataset samples, statistical tables, and graphs with algorithms and computational methods for developing new applications in healthcare informatics Unique case study approach provides readers with insights for practical clinical implementation

Our Angry Earth

Our Angry Earth

“A lucid overview of [environmental] problems and a compelling call to action.” —Publishers WeeklyFrom two of science fiction’s most celebrated and brilliant minds—Isaac Asimov and Frederik Pohl—comes the second edition of Our Angry Earth, a comprehensive analysis of today's environmental threats and a guide on how we can heal our planet, with an introduction and afterword from New York Times bestselling author Kim Stanley Robinson.Our Angry Earth provides a candid picture of the present and many possibilities for a better, cleaner future. From the greenhouse effect and depletion of our ozone layer to nuclear waste and species extinction, Asimov and Pohl not only present accessible explanations of complex scientific processes but ways we can improve our behavior and relationship with the planet, whether it be involvement in social activism or individual lifestyle changes.Kim Stanley Robinson, author of New York Times bestsellers 2312, New York 2140, and the internationally renowned Mars trilogy, brings his decades-spanning expertise in climate change to Our Angry Earth’s introduction and afterword.At the Publisher's request, this title is being sold without Digital Rights Management Software (DRM) applied.

World Biodiesel Policies and Production

World Biodiesel Policies and Production

This book presents the evolution of biodiesel technologies along with government policies of major biodiesel producing countries with their backgrounds, impacts, changes, and other energy forms. Biodiesel feedstock and biodiesel production technologies including green algae and methanol are presented as separate topics. Changes in the feedstock types and the corresponding technologies are presented, and their impacts on the biodiesel policies are explained. The life cycle analysis (LCA) in research and policy design of biodiesel is discussed and the findings are given for different feedstocks in terms of greenhouse gases, energy, and other impact categories.

Deregulated Electricity Market

Deregulated Electricity Market

Energy demand will increase by 70% by the year of 2030, and with the continual day-by-day depletion of traditional energy sources, there is a vast need to continue the development of dependable renewable energy sources that are locally available and that enhance energy generation efficiency. This important resource presents the topical issues of the deregulated electricity market, focusing on the integration of renewable sources with engineering approaches.The volume identifies and explores the deregulated electricity markets and looks at different renewable generation techniques and their operation and control issues. It considers the various power quality issues with renewable energy generation interfaced with smart grids and their solution techniques. It also addresses the various integration challenges of energy storage systems and energy management of electric vehicles in the smart grid environment. Topics include methods for frequency, angle, and voltage monitoring in smart grids; load frequency and voltage control pricing; grid integration of wind energy generation systems; tracking and management techniques; performance analysis; and more.This volume is an important resource for scientists, researchers, students, and academicians across the globe concerned with adopting and implementing novel research on smart power grids and renewable energy systems.

Biotechnology of Emerging Microbes

Biotechnology of Emerging Microbes

Biotechnology of Emerging Microbes: Prospects for Agriculture and Environment provides the latest developments of leading biotechnologists and bioengineers. The book covers various aspects of microbes mediated rhizosphere, biosphere, environmental, and ecosystem biotechnology, and focuses on the restoration and management of the rhizosphere, the biosphere, and the ecosystem with microbes for a sustainable future. It is designed to address various technical and application details of microorganisms and their products in biotechnology and bioengineering approaches. Users will find up-to-date knowledge that is beneficial to beginners, researchers, students, scientists, engineers, and industry stakeholders who can support the management of ecosystems through the use of microbes. Planet Earth is undergoing an accelerated process of change associated with a wide range of anthropogenic phenomena. The future of these changes is uncertain, but there is general agreement that this negative development might be detrimental to our own survival. Although different environmental engineering strategies have been developed, none of them seem to address carbon dioxide accumulation, biosphere, and ecosystem safety. The rapidly increasing potential for the development of living systems through the biotechnology and bioengineering of microbes is a sustainable alternative to address safety issues. - Addresses various technical and application details of microorganisms and their products for biotechnology and bioengineering approaches - Brings together the ideas and latest developments of leading biotechnologists and bioengineers - Covers various aspects of microbes mediated rhizosphere, biosphere, environmental, and ecosystem biotechnology

Crop Production Technologies for Sustainable Use and Conservation

Crop Production Technologies for Sustainable Use and Conservation

Crop Production Technologies for Sustainable Use and Conservation:Physiological and Molecular Advances presents an abundance of research on important and new production technologies for the successful sustainable production of major crops. The volume covers most of the major crops used the production of food, sugar, and commercial fiber. With the focus on sustainability and conservation issues in crop production, the chapters present molecular and physiological research and innovations for increasing yield, quality, and safety while also taking into considering increasing demand, diminishing water and land resources, and the agricultural consequences of climate change on crop production.The major crops discussed include wheat, mungbean, cotton, jute, sugarcane, eggplant, Solanum (such as potatoes and tomatoes), peppers, okra, fruits such as apples and pears, and more. The chapters report on new developments and research on production techniques related to various fertilizers, biosystematics and molecular biology of various crops, and building resistance to climatic change, including drought tolerance, salinity stresses, and more.

Functionalized Graphene Nanocomposites and Their Derivatives (Enhanced Edition)

Functionalized Graphene Nanocomposites and Their Derivatives (Enhanced Edition)

Functionalized Graphene Nanocomposites and Their Derivatives: Synthesis, Processing and Applications explains how the functionalization technique is used to create graphene nanocomposites, also exploring its current uses in industrial applications. Graphene-based nanocomposites are one of the major advancements in polymer-based materials, thus the synthesis, nanoscale dimensions, high aspect ratio, mechanical, electrical and thermal properties of graphene and its derivative have all been major areas of research in the last decade. This important reference covers these updates and is a critical book for those working in the fields of materials processing and characterization. Explains how graphene is functionalized and used in the fabrication of nanocomposites for a range of applications Explores why the properties of functionalized graphene make it such a useful, versatile material Describes, in detail, the functionalization process for utilization in graphene

Engineered Carbon Nanotubes and Nanofibrous Material

Engineered Carbon Nanotubes and Nanofibrous Material

Carbon nanotubes, with their extraordinary engineering properties, have garnered much attention in the past 10 years. Because of the broad range of potential applications, the scientific community is more motivated than ever to move beyond basic properties and explore the real issues associated with carbon nanotube-based applications. Presenting up-to-date literature that presents the current state of the science, this book, Engineered Carbon Nanotubes and Nanofibrous Material: Integrating Theory and Technique, fully explores the development phase of carbon nanotube-based applications. It looks at carbon nanotubes and their applications in diverse areas of science and engineering and considers environmental engineering applications as well. This volume is a valuable resource for engineers, scientists, researchers, and professionals in a wide range of disciplines whose focus remains on the power and promise of carbon nanotubes.

Advanced Polymeric Materials

Advanced Polymeric Materials

Recent advances in polymer research has led to the generation of high quality materials for various applications in day to day life. The synthesis of new functional monomers has shown strong potential in generating novel polymer materials, with improved properties.Advanced Polymeric Materials includes fundamentals and numerous examples of polymer blend preparation and characterizations. Developments in blends, polymer nanocomposites and its various characterization techniques are highlighted in the book.

Symbolic Logic

Symbolic Logic

The book described logic is expressed in terms of symbols; syllogisms and the sorites are diagrammed; logic becomes a game played with two diagrams and a set of counters.

Innovative Food Science and Emerging Technologies

Innovative Food Science and Emerging Technologies

This volume covers many new trends and developments in food science, including preparation, characterization, morphology, properties, and recyclability. The volume considers food quality, shelf life, and manufacturing in conjunction with human nutrition, diet, and health as well as the ever-growing demand for the supply and production of healthier foods.Distinguished scientists specializing in various disciplines discuss basic studies, applications, recent advances, difficulties, and breakthroughs in the field. The volume includes informative discussions and new research on food formulations, manufacturing techniques, biodegradably flexible packaging, packaged foods, beverages, fruits and vegetable processing, fisheries, milk and milk products, frozen food and thermo processing, grain processing, meat and poultry processing, rheological characteristics of foods, heat exchangers in the food industry, food and health (including natural cures and food supplements), spice and spice processing, and more.

Avventure nella mente degli altri

Avventure nella mente degli altri

Qual è la differenza tra bloccarsi e farsi prendere dal panico? Perché ci sono decine di varietà di senape, ma solo una di ketchup? Che cosa ci insegnano i giocatori di football sui criteri usati per assumere gli insegnanti? Che cosa ci dicono le tinture per capelli sulla storia del XX secolo? Malcolm Gladwell è autore di libri che hanno radicalmente cambiato il nostro modo di comprendere il mondo e noi stessi: che analizzi i processi grazie ai quali siamo in grado di prendere decisioni immediate (come In un batter di ciglia) o consideri le ragioni che stanno alla base del successo (come in Fuoriclasse), Gladwell mostra un talento straordinario nell'indagare aspetti della vita apparentemente banali per trasformarli in piccole teorie rivoluzionarie. "Di tutte le persone che incontrerete in questo libro, ben poche sono potenti, o anche solo famose. Se vuoi trovare una storia non devi partire dall'alto. Devi partire dal mezzo, perché è la gente che sta nel mezzo a fare davvero le cose nel mondo." Avventure nella mente degli altri presenta diciannove brevi saggi in cui l'autore dà sfogo alla sua insaziabile curiosità per il quotidiano che lo circonda. Troviamo la storia agrodolce dell'inventore della pillola anticoncezionale, che tentò invano di rendere bene accetta la sua creatura alla Chiesa cattolica, e l'avventura nel marketing di Howard Moskowitz, quando scoprì il principio che "la gente non sa che cosa vuole" e lo applicò alle ricerche di mercato nel campo dei sughi pronti. Facciamo la conoscenza di Ron Popeil, il re della cucina americana, mentre vende girarrosti, e indoviniamo i segreti di Cesar Millan, "l'uomo che sussurra ai cani", capace di calmare animali selvaggi con il tocco della mano. Che le teorie di Gladwell vi convincano o meno non è importante, "perché la buona scrittura riesce o fallisce non a seconda della sua capacità di convincere. Riesce o fallisce a seconda della sua capacità di farvi intravedere cosa c'è nella testa di un altro".

Biological Processing of Solid Waste

Biological Processing of Solid Waste

Offering a comprehensive approach, this title covers fundamentals, technologies, and management of biological processing of solid waste. It discusses kinetic modeling and synergistic impact evolution during bioprocessing of solid waste, environmental impacts such as greenhouse gas emission from biological processing of solid waste, energy recovery from solid waste, and biodrying of solid waste. It also presents cases and challenges from different countries, successful business models, and economic analyses of various processing options.Aimed at researchers and industry professionals in solid and hazardous waste management, this title offers a wealth of knowledge to help readers understand this increasingly important area.

Thermal Energy Systems

Thermal Energy Systems

The text provides in-depth knowledge about recent advances in solar collector systems, photovoltaic systems, the role of thermal energy systems in buildings, phase change materials, geothermal energy, biofuels, and thermal management systems for EVs in social and industrial applications. It further aims toward the inclusion of innovation and implementation of strategies for CO2 emission reduction through the reduction of energy consumption using conventional sources.This book: Presents the latest advances in the field of thermal energy storage, solar energy development, geothermal energy, and hybrid energy applications for green development Highlights the importance of innovation and implementation of strategies for CO2 emission reduction through the reduction of energy consumption using sustainable technologies and methods Discusses design development, life cycle assessment, modelling and simulation of thermal energy systems in detail Synergize exploration related to the various properties and functionalities through extensive theoretical and numerical modelling present in the energy sector Explores opportunities, challenges, future perspectives and approaches toward gaining sustainability through renewable energy resources The text discusses the fundamentals of thermal energy and its applications in a comprehensive manner. It further covers advancements in solar thermal and photovoltaic systems. The text highlights the contribution of geothermal energy conversion systems to sustainable development. It showcases the design and optimization of ground source heat pumps for space conditioning and presents modelling and simulation of the thermal energy systems for design optimization. It will serve as an ideal reference text for senior undergraduate, graduate students and academic researchers in the fields of mechanical engineering, environmental engineering and energy engineering.

Pistis: Reology, The Three Grand Illusions, and The Power To Choose

Pistis: Reology, The Three Grand Illusions, and The Power To Choose

This book is about reality. It’s about drawing conclusions about our existence based on obvious, yet ignored principles that are fundamental to all the experience we know, including the experience of ourselves. It offers viable clues to understanding the who, what, and why of what mankind is, as well as all that exists.This book is a journey. In its 169 pages you will find reason for infinite ponder and wonder. It is said that truth can often be stranger than fiction. No where will you find this more true then in the pages that follow.

Computational Intelligence and Deep Learning Methods for Neuro-rehabilitation Applications (Enhanced Edition)

Computational Intelligence and Deep Learning Methods for Neuro-rehabilitation Applications (Enhanced Edition)

Computational Intelligence and Deep Learning Methods for Neuro-rehabilitation Applications explores the different possibilities of providing AI based neuro-rehabilitation methods to treat neurological disorders. This book provides in-depth knowledge on the challenges and solutions associated with the different varieties of neuro-rehabilitation through the inclusion of case studies and real-time scenarios in different geographical locations. Beginning with an overview of neuro-rehabilitation applications, the book discusses the role of machine learning methods in brain function grading for adults with Mild Cognitive Impairment, Brain Computer Interface for post-stroke patients, developing assistive devices for paralytic patients, and cognitive treatment for spinal cord injuries.  Topics also include AI-based video games to improve the brain performances in children with autism and ADHD, deep learning approaches and magnetoencephalography data for limb movement, EEG signal analysis, smart sensors, and the application of robotic concepts for gait control.Incorporates artificial intelligence techniques into neuro-rehabilitation and presents novel ideas for this processProvides in-depth case studies and state-of-the-art methods, along with the experimental studyPresents a block diagram based complete set-up in each chapter to help in real-time implementation

Fractional Order Systems and Applications in Engineering (Enhanced Edition)

Fractional Order Systems and Applications in Engineering (Enhanced Edition)

Fractional Order Systems and Applications in Engineering presents the use of fractional calculus (calculus of non-integer order) in the description and modelling of systems and in a range of control design and practical applications. The book covers the fundamentals of fractional calculus together with some analytical and numerical techniques, and provides MATLAB® codes for the simulation of fractional-order control (FOC) systems. The use of fractional calculus can improve and generalize well-established control methods and strategies. Many different FOC schemes are presented for control and dynamic systems problems. These extend to the challenging control engineering design problems of robust and nonlinear control. Practical material relating to a wide variety of applications including, among others, mechatronics, civil engineering, irrigation and water management, and biological systems is also provided. All the control schemes and applications are presented with either system simulation results or real experimental results, or both. Fractional Order Systems and Applications in Engineering introduces readers to the essentials of FOC and imbues them with a basic understanding of FOC concepts and methods. With this knowledge readers can extend their use of FOC in other industrial system applications, thereby expanding their range of disciplines by exploiting this versatile new set of control techniques. Provides the most recent and up-to-date developments on the Fractional-order Systems and their analyzing process Integrates recent advancements of modeling of real phenomena (on Fractional-order Systems) via different-different mathematical equations with demonstrated applications in numerous seemingly diverse and widespread fields of science and engineering Provides readers with illustrative examples of how to use the presented theories of Fractional-order Systems in specific cases with associated MATLAB code

The Works of Lord Byron. Vol. 2

The Works of Lord Byron. Vol. 2

In compiling the Introductions, the additional notes, and footnotes, I have endeavoured to supply the reader with a compendious manual of reference. With the subject-matter of large portions of the three distinct poems which make up the five hundred stanzas of Childe Harold's Pilgrimage every one is more or less [vii]familiar, but details and particulars are out of the immediate reach of even the most cultivated readers. The poem may be dealt with in two ways. It may be regarded as a repertory or treasury of brilliant passages for selection and quotation; or it may be read continuously, and with some attention to the style and message of the author. It is in the belief that Childe Harold should be read continuously, and that it gains by the closest study, reassuming its original freshness and splendour, that the text as well as Byron's own notes have been somewhat minutely annotated.